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Cystic Fibrosis [CF] – Cause and Symptoms

July 1, 2009


Cystic fibrosis [CF] is a genetic discrepancy and it affects secretion glands of sweat and mucus in an individual. Cystic fibrosis negatively impacts on the organs like lungs, pancreas, intestines, liver, sex organs and sinuses, etc.

The key role of mucus in our boy is to retain the moist base of the organs’ linings in order to prevent the linings from being infected or getting dried. It is a watery substance; however, in case of the Cystic fibrosis patient mucus body turns into thick and sticky substance.

The thick substantial presence of mucus tends to block air passage of lungs, pancreatic duct and tubes and results in multiple disorders and discomforts for the affected persons.

In case of diagnosis of Cystic fibrosis [CF], a sweat test is done to confirm the disorder. Cystic fibrosis is also known as cystic fibrosis of pancreas, Pancreas fibrocystic disease, pancreatic cystic fibrosis, Mucoviscidosis of the pancreas, Mucoviscidosis, etc.

The main trigger behind the cystic fibrosis is purely genetic and the name of the malfunctioning gene is Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene which is held responsible for the production of a specific protein. This particular gene controls the movement of water and salt in and out of the body cells. In the affected patients of Cystic Fibrosis this gene do not work properly which result in thick and sticky formation of mucus; CF affected patients also suffer from very salty sweating.

Babies at the time of conception inherit two CFTR genes, each from their parents. However, unfortunately, if both the genes turn to be malfunctioning, the baby becomes the victim of Cystic Fibrosis disease. If only one gene is abnormal or malfunctioning, the baby skips the induction issue of Cystic Fibrosis disease.

The Symptoms for the Cystic fibrosis (CF) affected patients are generally same because of their single point of discrepancy. Frequent coughing with thick sputum, frequent infection of pneumonia, and bronchitis are the main suffering symptoms of this disease which may impact in permanent inflammation and damage to lungs.

Frequent bout of dehydration, salty tasting skin, infertility in case of men, recurring problem diarrhea or bulky, greasy, and fouls smelling stools are the additional symptoms for cystic fibrosis disease. Cystic fibrosis [CF] affected patients suffer from frequent stomach pain, discomfort and flatulence in digestive system.


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